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1 2 The test is simple, non-invasive, and is performed after a short period of fasting (typically 812 hours). This is a test for bacterial overgrowth using glucose. A hydrogen breath test (or HBT) is used as a diagnostic tool for small intestine bacterial overgrowth and carbohydrate malabsorption, such as lactose, fructose, and sorbitol malabsorption. Original version 2015 ( 1st generation)ģ. How is SIBO diagnosed The most common way to diagnose SIBO is by undergoing a Hydrogen breath test. IBS chek - Commonwealth Diagnostics International. Updated and improved version with greater specificity. Diagnoses Food Poisoning as the cause of SIBO/IBS (if test is positive)ġ. Deficient Migrating Motor Complex/Motility in the small intestine is the physiologic underlying cause of SIBO (if test is positive) Diagnose underlying cause and cause of SIBO if test is positive Avoids potentially unnecessary colonoscopyģ. Rules out Inflammatory Bowel Disease with 98% probability (if positive & using IBS Smart blood testspecifically) Screening test because food poisoning is estimated to account for a majority of IBS/SIBO. From food poisoning, but not other causes. A screening blood test for IBS / Diagnose SIBO (if positive) If Cdt B alone is Positive: If means there is no autoimmunity and the prognosis is shorter/more favorable.ġ. Prokinetics to help stimulate the migrating motor complex are indicated. If Vinculin alone is Positive: It means there is autoimmunity and the prognosis is longer/more complicated. The breath test diagnoses SIBO from all causes, whereas the IBS Blood test only detects SIBO caused from food poisoning. If the test is Negative (both antibodies): A SIBO breath test is needed to complete the investigation of SIBO (see below). A SIBO breath test is then recommended to help choose treatment type and duration, which depend on gas type and amount (shown with a breath test - see below). It also rules out Inflammatory Bowel Disease with 98% probability (if using IBS Smart blood testspecifically - see test Availability below). If the test is Positive (both antibodies): It means the migrating motor complex waves in the small intestine are deficient and can not clear bacteria out (= SIBO). Two versions of this test have been correlated with the diarrhea and mixed type of SIBO.( 1, 2) Constipation cases caused by food poisoning are also possible, but less likely. Food poisoning is thought to be the most common cause of SIBO (& IBS) and is also known as travelers diarrhea and stomach flu. It detects SIBO that developed after bacterial food poisoning through an autoimmune process.
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The IBS Blood test measures antibodies against the bacterial toxin Cytolethal Distending Toxin B (CdtB) and the small intestine nerve protein Vinculin.